We are studying a combination of treatments for patients with inoperable intra-hepatic cholangiocarcinoma. The goal is to see if these treatments can improve survival and quality of life.
We are testing whether subcutaneous methotrexate can improve skin symptoms in adults with moderate to severe atopic dermatitis compared to a placebo. The study also examines safety and quality of life for participants.
We are studying a new treatment called disitamab vedotin for adults with advanced solid tumors that express HER2 and have been previously treated. The trial aims to evaluate its effectiveness and safety.
We are studying how somatostatin receptors behave in metastatic breast cancer using DOTATOC-68Ga PET scans. This may help us understand the disease better and improve future imaging techniques.
We are studying a new injection treatment for children with severe to profound hearing loss due to Otoferlin gene mutations. The trial will assess both the safety and effectiveness of this treatment.
We are studying if adding radiotherapy to pembrolizumab helps patients with limited spread of head and neck cancer live longer and feel better. This trial focuses on those with a specific type of cancer and aims to compare treatment effects and safety.
We are studying whether using protamine sulfate can reduce complications like strokes and bleeding during heart valve surgery. This trial is for patients with aortic stenosis undergoing transcatheter aortic valve implantation.
We are studying whether ruxolitinib, combined with standard care, can improve organ function and survival in critically ill patients with acquired hemophagocytic syndrome. This trial also looks at the safety and effects of the drug on various health markers.
We are investigating whether injecting botulinum toxin A before surgery helps reduce complications and improve recovery for patients with large incisional hernias. This study compares the effects of BTA to a placebo injection.
We are comparing two treatments to prevent graft versus host disease in elderly patients with acute myeloid leukemia or myelodysplastic syndrome receiving stem cell transplants. The goal is to find out which treatment leads to better outcomes after transplantation.
We are exploring whether Botox can effectively reduce pain in patients with trigeminal neuralgia compared to a placebo. Additionally, we’re investigating if specific biomarkers can help predict treatment response.
We are investigating how levels of ficolin-2 relate to inflammation in the carotid arteries and brain in patients who have had a stroke or transient ischemic attack. This research may help us understand the underlying causes of these conditions better.
We are studying whether starting vasopressor therapy early helps hypotensive patients in the emergency department recover faster than standard fluid therapy. This may reduce the need for intensive care admission.
We are studying the safety and effectiveness of a new treatment combining THIO and cemiplimab for people with advanced non-small cell lung cancer. This trial aims to find out if this combination works better than THIO alone for patients who have already been treated.
We are assessing the effectiveness and safety of a combination treatment for adults with recurring chronic lymphocytic leukemia. This study aims to understand how well the treatment works and what side effects may occur.
We are studying a combination of two medications for people with advanced liver cancer who have not had prior treatment. The goal is to find the best dose and assess safety and effectiveness.
We are studying whether modified autologous leukocyte cells can help patients recover kidney function after developing acute kidney injury following cardiac surgery. The trial will also assess the safety of this new treatment.
We are studying the use of two imaging agents during surgery for colorectal liver metastases to see if they help surgeons remove cancerous tissue more effectively. This trial aims to improve surgical accuracy and patient outcomes.
We are investigating whether adding pembrolizumab to chemotherapy improves outcomes for patients with early-stage triple-negative breast cancer based on their tumor-infiltrating lymphocyte levels. This study also looks at the safety and quality of life for participants.
We are investigating whether apomorphine can help patients with disorders of consciousness. The study also aims to identify which patients may respond best to this treatment.