Search Clinical Trials in the European Union

Duration
Visits
Phase
Intake methods
Benefits
Drugs
Locations
Clinical Specialty
2201-2220 of 3,900 trials

Pancreatic Exocrine Insufficiency: Creon® Therapy

We are studying how well Creon® helps patients with pancreatic exocrine insufficiency after surgery. The goal is to see if it improves symptoms and nutritional health.

Pancreatic Exocrine Insufficiency6-12 monthsConfirmation phase (III)6-10 visitsNo PlaceboStandard MedicinesCost ReimbursementGastroenterologyInternal Medicine

Head and Neck or Liver Cancer: Testing New Drug Combinations

We are studying whether combinations of BI 765063, ezabenlimab, chemotherapy, cetuximab, and BI 836880 can help people with head and neck or liver cancer. This research aims to find more effective treatment options.

Head and Neck Squamous Cell Carcinoma (HNSCC)Hepatocellular Carcinoma>2 yearsSafety phase (I)Oncology

Advanced Solid Tumors: INCB123667 Study

We are testing a new drug, INCB123667, alone and with other cancer therapies for people with advanced solid tumors. The goal is to understand its effects and potential benefits in treating these cancers.

Advanced Cancer>2 yearsSafety phase (I)Oncology

Squamous Cell Carcinoma of the Penis: Lymphadenectomy and Chemotherapy Study

We are studying a treatment combining surgery and chemotherapy for patients with inguinal lymph node metastases. The goal is to see if this approach improves survival and reduces the chance of cancer returning.

Penis Cancer>2 yearsEfficacy phase (II)No PlaceboStandard MedicinesOncology

Heart Attack Treatment: Cangrelor and Bivalirudin

We are studying a new combination of medications for patients with heart attacks in critical condition. The goal is to see if this treatment can prevent blood clots while keeping bleeding risks low.

Cardiogenic Shock>2 yearsEfficacy phase (II)No PlaceboStandard MedicinesCardiologyInternal Medicine

Anorexia Nervosa: Sertraline Pharmacokinetics Study

We are exploring how a single dose of sertraline is processed in the body of female patients with anorexia nervosa compared to healthy women. This study may help improve treatment approaches for anorexia.

Anorexia Nervosa>2 yearsSafety phase (I)Psychiatry

Lutetium Lu 177 Edotreotide for Pediatric Tumors

We are studying a new targeted therapy for children with somatostatin receptor-positive tumors to find the right dose and evaluate its safety. This trial will also look at how well the treatment works compared to standard care.

RhabdomyosarcomaLymphomaNeuroendocrine Tumor>2 yearsSafety phase (I)No PlaceboInvestigational MedicinesOncologyPediatrics

Diffuse Large B-Cell Lymphoma: Axicabtagene Ciloleucel Study

We are studying a new treatment for patients with late relapse of diffuse large B-cell lymphoma to see if it improves their condition and quality of life. The trial also looks at the safety of this treatment.

Recurrent B-cell Non-Hodgkin's Lymphoma>2 yearsEfficacy phase (II)No PlaceboStandard MedicinesHematologyOncology

Advanced Solid Tumors: RO7567132 and Atezolizumab Study

We are investigating the safety and effectiveness of RO7567132 alone and with Atezolizumab in patients with advanced or metastatic solid tumors. This study aims to learn how the body processes the drug and its potential benefits.

Advanced and Metastatic Solid Tumors>2 yearsSafety phase (I)Oncology

Vaginal Progesterone for IVF: Improving Live Birth Rates

We are studying whether vaginal progesterone helps women achieve live births after frozen embryo transfer. The trial compares outcomes between those receiving progesterone and those who do not.

Infertility≤3 monthsMonitoring phase (IV)No PlaceboStandard MedicinesEndocrinologyGynecology and Obstetrics

Microvillus Inclusion Disease: Crofelemer Study

We are testing the safety and effects of a new oral solution, Crofelemer, in children with Microvillus Inclusion Disease. The study aims to see if it can help reduce symptoms and improve health compared to a placebo.

Microvillous Inclusion Disease6-12 monthsEfficacy phase (II)Investigational MedicinesPartially RemoteGastroenterologyPediatrics

Lung Fibrosis: Nerandomilast Study

We are testing whether nerandomilast can improve lung function in people with lung fibrosis related to rheumatic diseases. The study will also look at safety, including the risk of infections.

Systemic Autoimmune Rheumatic Diseases associated Interstitial Lung Diseases6-12 monthsConfirmation phase (III)6-10 visitsPost-Trial Drug AccessInvestigational MedicinesPulmonologyRheumatology

Prostate Cancer Diagnosis: 18F-PSMA PET/MRI Study

We are testing a new imaging method to see how well it identifies clinically significant prostate cancer. This may help improve diagnosis accuracy for patients.

Prostate Cancer>2 yearsEfficacy phase (II)No PlaceboStandard MedicinesOtolaryngologyUrology

Vulvar Squamous Cell Carcinoma: Pembrolizumab Study

We are studying whether Pembrolizumab can help shrink tumors in patients with vulvar squamous cell carcinoma before surgery. This trial also looks at how the treatment affects the immune system.

Vulvar Squamous Cell Carcinoma1-2 yearsEfficacy phase (II)6-10 visitsNo PlaceboStandard MedicinesGynecology and ObstetricsOncology

IgG4-Related Disease: Abatacept Treatment Study

We are investigating whether abatacept can help reduce the risk of disease recurrence in people with IgG4-related disease. This study aims to provide insights into a new treatment option for managing this condition.

IgG4-Related Disease>2 yearsEfficacy phase (II)No PlaceboStandard MedicinesInternal MedicineRheumatology

Generalized Myasthenia Gravis: DNTH103 Treatment Study

We are testing a new treatment called DNTH103 for adults with generalized myasthenia gravis. The study aims to evaluate its safety, tolerability, and effectiveness in managing symptoms.

Myasthenia Gravis3-6 monthsEfficacy phase (II)11-15 visitsPost-Trial Drug AccessInvestigational MedicinesNeurology

Tocolysis for Preterm Premature Rupture of Membranes

We are studying whether a short-term treatment can help pregnant individuals with PPROM before 34 weeks of gestation. The goal is to see if it reduces complications for mothers and their babies.

Complicated ChildbirthConfirmation phase (III)Standard MedicinesGynecology and Obstetrics

Kidney Health: CO2 Injection in Vascular Procedures

We are testing a new method using Carbon Dioxide instead of traditional contrast media for patients at risk of kidney injury during vascular interventions. This study aims to see if it can help prevent serious kidney problems after the procedure.

Peripheral Arterial Disease (PAD)>2 yearsConfirmation phase (III)≤5 visitsNo PlaceboInvestigational MedicinesPartially RemoteCardiologyNephrology

Shingrix Vaccine: Safety in Psoriasis and Psoriatic Arthritis

We are studying the safety and immune response of the Shingrix vaccine in patients with psoriasis or psoriatic arthritis. Our goal is to see how the vaccine affects disease activity and to monitor any side effects.

Psoriatic ArthritisPsoriasis Vulgaris>2 yearsMonitoring phase (IV)No PlaceboStandard MedicinesPartially RemoteAllergologyDermatology

Advanced Cancers with BRAF Mutations: Sorafenib and Trametinib Study

We are testing a combination of two medications for patients with advanced-stage cancers that have BRAF mutations. The goal is to find the best dose and understand how well this treatment works and its safety.

Advanced-Stage Cancer with BRAF Mutation>2 yearsSafety phase (I)Efficacy phase (II)11-15 visitsNo PlaceboInvestigational MedicinesOncology