Search Clinical Trials in the European Union

3-6 months
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281-300 of 331 trials

Ulcerative Colitis: Tofacitinib's Impact on Blood Clotting

We are studying how tofacitinib affects blood clotting and platelet function in patients with ulcerative colitis. This trial also compares its effects to other treatments and collects samples for future research.

Ulcerative Colitis3-6 monthsMonitoring phase (IV)Post-Trial Drug AccessNo PlaceboStandard MedicinesGastroenterologyHematology

Ischemic Stroke: Thrombolytic Therapy with rtPA

We are studying a new treatment for patients with acute ischemic stroke who are on blood thinners. The goal is to see if this therapy improves recovery compared to a placebo after reversing the blood thinner's effects.

Ischaemic Stroke3-6 monthsEfficacy phase (II)≤5 visitsStandard MedicinesPartially RemoteInternal MedicineNeurology

Alzheimer's Disease: NSC001 Medication Study

We are investigating the safety and tolerability of a new medication, NSC001, for people with mild to moderate Alzheimer's disease. This study will help us learn more about how the medication works in the body.

Alzheimer's Disease3-6 monthsEfficacy phase (II)6-10 visitsInvestigational MedicinesNeurology

Dravet Syndrome: EPX-100 Treatment Study

We are testing a new medication, EPX-100, to see if it helps children and adults with Dravet Syndrome manage their seizures better than a placebo. This study aims to find out if this treatment can be a useful addition to their current care.

Dravet Syndrome3-6 monthsConfirmation phase (III)Post-Trial Drug AccessInvestigational MedicinesNeurologyPediatrics

Idiopathic Infertility: Metformin Treatment Study

We are investigating whether metformin can improve endometrial function in women with idiopathic infertility. This study aims to explore its effects on fertility and related biological markers.

Female Infertility3-6 monthsEfficacy phase (II)Standard MedicinesEndocrinologyGynecology and Obstetrics

Palmoplantar Pustulosis: Delgocitinib Cream Study

We are investigating whether delgocitinib cream can effectively treat adults with mild to severe palmoplantar pustulosis compared to a dummy cream. The study will also assess the safety and impact on quality of life.

Palmoplantar Pustulosis3-6 monthsEfficacy phase (II)6-10 visitsInvestigational MedicinesDermatology

Narcolepsy and Idiopathic Hypersomnia: ORX750 Study

We are testing a new medication, ORX750, to see if it is safe and well-tolerated in people with narcolepsy and idiopathic hypersomnia. This study will help us understand how the drug works in the body.

Narcolepsy with CataplexyIdiopathic Hypersomnia3-6 monthsEfficacy phase (II)≤5 visitsPost-Trial Drug AccessInvestigational MedicinesCost ReimbursementPartially RemoteNeurology

X-ALD: Pramipexole for Leg Symptoms

We are investigating whether pramipexole can help reduce restless leg symptoms in women with X-linked Adrenoleukodystrophy. This study aims to improve their sleep and walking performance.

X-linked AdrenoleukodystrophyRestless Legs Syndrome3-6 monthsMonitoring phase (IV)11-15 visitsNo PlaceboStandard MedicinesCost ReimbursementPartially RemoteNeurology

Gastric Cancer: Pre-operative Treatment with Capecitabine and Atezolizumab

We are studying a combination of chemotherapy and immunotherapy for patients with resectable gastric and GE-junction cancer. The goal is to see if this treatment is safe and effective in shrinking tumors before surgery.

Gastric Cancer3-6 monthsEfficacy phase (II)No PlaceboStandard MedicinesGastroenterologyOncology

Atopic Dermatitis: Investigational Compounds Study

We are evaluating new treatments for moderate to severe atopic dermatitis to see if they improve skin symptoms better than a placebo. The study also looks at the safety of these treatments.

Atopic Dermatitis3-6 monthsEfficacy phase (II)Investigational MedicinesAllergologyDermatology

Advanced Solid Tumors: Testing IPN01195

We are studying a new medicine called IPN01195 to see how safe it is and what the best dose is for adults with advanced solid tumors. This trial aims to understand its effects on tumor activity and how it works in the body.

Advanced Solid Tumour3-6 monthsSafety phase (I)Efficacy phase (II)≤5 visitsNo PlaceboStandard MedicinesCost ReimbursementOncology

Major Depressive Disorder: CYB003 Treatment Study

We are studying the effects of a new medication, CYB003, on symptoms of major depressive disorder in adults. This trial compares its effectiveness to a placebo to see if it may help improve mood and quality of life.

Major Depressive Disorder3-6 monthsConfirmation phase (III)6-10 visitsPost-Trial Drug AccessInvestigational MedicinesCost ReimbursementPartially RemotePsychiatry

Psoriatic Arthritis: Lutikizumab and Risankizumab Study

We are testing the effectiveness and safety of a combination of two medications for adults with active psoriatic arthritis. This study aims to see if the combination works better than each medication alone.

Psoriatic Arthritis3-6 monthsEfficacy phase (II)No PlaceboInvestigational MedicinesInternal MedicineRheumatology

Oligometastatic Prostate Cancer: Lu-PSMA and Radiotherapy Study

We are investigating whether combining Lu-PSMA with stereotactic radiotherapy improves survival and quality of life for patients with oligometastatic prostate cancer compared to radiotherapy alone.

Metastatic Prostate Cancer3-6 monthsEfficacy phase (II)No PlaceboStandard MedicinesOncologyUrology

Glioblastoma: Adding Zoledronic Acid to Treatment

We are studying whether adding zoledronic acid to standard chemotherapy can help improve survival and treatment response in patients with glioblastoma. We also want to assess its safety and tolerability.

Glioblastoma3-6 monthsEfficacy phase (II)6-10 visitsNo PlaceboStandard MedicinesPartially RemoteNeurologyOncology

Type 1 Diabetes: NNC0194-0499 and Semaglutide Study

We are exploring how a new treatment and its combination with semaglutide can help control blood sugar in people with type 1 diabetes. This study aims to improve management options for those living with this condition.

Type 1 Diabetes3-6 monthsSafety phase (I)DiabetologyEndocrinology

Reducing Complications After Pancreatoduodenectomy: HOP Bundle Study

We are investigating whether a combination of hydrocortisone, octreotide, and a teres ligament patch can help prevent major complications in patients undergoing high-risk pancreatoduodenectomy. This study also looks at its effect on specific complications like pancreatic fistulas.

Resectable Pancreatic Cancer3-6 monthsMonitoring phase (IV)No PlaceboStandard MedicinesInternal MedicineOncologyOrthopedics and Traumatology

GSK4418959 for Solid Tumors: A New Treatment Approach

We are investigating the safety and early effectiveness of the DNA-repair inhibitor GSK4418959 in adults with specific solid tumors. This study looks at the drug alone and with other cancer treatments to see how well it works.

Colorectal Cancer3-6 monthsSafety phase (I)Efficacy phase (II)No PlaceboInvestigational MedicinesCost ReimbursementPartially RemoteOncology

Sickle Cell Disease: Tebapivat Study

We are investigating a new medication, tebapivat, to see if it helps improve anemia in people with sickle cell disease. The study will also look at its safety and effects on fatigue and pain.

Sickle Cell Disease3-6 monthsEfficacy phase (II)6-10 visitsPost-Trial Drug AccessInvestigational MedicinesCost ReimbursementPartially RemoteHematologyInternal Medicine

Chronic Heart Failure: Vitamin D and Oral Iron Study

We are studying whether vitamin D combined with oral iron can improve symptoms in patients with chronic heart failure and iron deficiency. This trial compares it to standard intravenous iron treatment to see which is more effective.

Chronic Heart FailureIron Deficiency3-6 monthsMonitoring phase (IV)≤5 visitsNo PlaceboInvestigational MedicinesCardiologyInternal Medicine