Search Clinical Trials in the European Union

3-6 months
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81-100 of 331 trials

Alcohol Dependence: Sodium Oxybate Study

We are investigating whether Sodium Oxybate can help reduce alcohol consumption in people with high drinking risk levels. This study aims to support individuals in maintaining abstinence from alcohol.

Alcohol Addiction3-6 monthsConfirmation phase (III)6-10 visitsStandard MedicinesPsychiatry

Ovarian Stimulation in Older Women: INOVEE Study

We are comparing two doses of a fertility medication to see which produces more healthy embryos in older women undergoing fertility treatment. This study aims to improve outcomes for women trying to conceive.

Female Infertility3-6 monthsMonitoring phase (IV)No PlaceboStandard MedicinesEndocrinologyGynecology and Obstetrics

Labor Induction: Outpatient vs. Inpatient Methods

We are studying whether inducing labor at home is as safe and effective as doing it in a hospital. We want to understand the costs and experiences of women and healthcare staff in both settings.

Induction of Labour3-6 monthsMonitoring phase (IV)No PlaceboStandard MedicinesGynecology and Obstetrics

Genitourinary Syndrome of Menopause: Cellular Matrix Treatment

We are studying a new treatment combining platelet-rich plasma and hyaluronic acid for women with genitourinary syndrome of menopause. This trial compares its effects to a standard estrogen gel to see which works better for symptom relief.

Genitourinary Syndrome of Menopause3-6 monthsMonitoring phase (IV)≤5 visitsNo PlaceboInvestigational MedicinesGynecology and Obstetrics

ACP-204 for Alzheimer's Disease Psychosis

We are testing the effects of ACP-204 in adults with Alzheimer's disease psychosis to see if it helps improve symptoms compared to a placebo.

Alzheimer's DiseaseAlzheimer's Disease Psychosis3-6 monthsEfficacy phase (II)6-10 visitsPost-Trial Drug AccessInvestigational MedicinesCost ReimbursementPartially RemoteNeurologyPsychiatry

Oral Vancomycin for Primary Sclerosing Cholangitis

We are studying whether oral vancomycin can improve liver health in adults and young patients with Primary Sclerosing Cholangitis. The trial will also look at the safety of the treatment and its effects on related health conditions.

Primary Sclerosing Cholangitis3-6 monthsEfficacy phase (II)Standard MedicinesGastroenterologyHepatology

Hip Replacement Surgery: Shorter Blood Thinner Duration

We are studying whether a shorter course of blood-thinning medication after hip replacement surgery is as effective as the standard duration in preventing blood clots. This trial aims to improve recovery and safety for patients.

Hip Osteoarthritis3-6 monthsConfirmation phase (III)Standard MedicinesHematologyOrthopedics and Traumatology

Vertebral Osteomyelitis: Early Oral Antibiotics Study

We are investigating if switching to oral antibiotics after one week is as effective as continuing intravenous treatment for pyogenic vertebral osteomyelitis. This study will also assess safety, hospital stays, and quality of life for patients.

Pyogenic Vertebral Osteomyelitis3-6 monthsMonitoring phase (IV)No PlaceboStandard MedicinesInfectious DiseasesOrthopedics and TraumatologyRheumatology

Rheumatoid Arthritis: MethMax Trial

We are studying how well methotrexate works for people with active rheumatoid arthritis. The goal is to see if it helps more patients reach remission or low disease activity compared to current treatments.

Rheumatoid Arthritis3-6 monthsMonitoring phase (IV)6-10 visitsNo PlaceboStandard MedicinesInternal MedicineRheumatology

Progesterone for Preventing Preterm Birth in Women with Placenta Previa

We are studying whether progesterone can help reduce the risk of preterm birth in women diagnosed with placenta previa. This trial will look at various outcomes, including the timing of birth and any side effects for mothers and babies.

Placenta Previa3-6 monthsMonitoring phase (IV)No PlaceboStandard MedicinesGynecology and ObstetricsPediatrics

Pulmonary Embolism: Surveillance vs. Anticoagulation

We are studying whether monitoring without blood thinners is as safe and effective as using them for low-risk patients with isolated subsegmental pulmonary embolism. This trial will also assess side effects and quality of life for participants.

Isolated Subsegmental Pulmonary Embolism3-6 monthsMonitoring phase (IV)≤5 visitsStandard MedicinesPartially RemoteCardiologyPulmonology

Hot Flashes After Breast Cancer: Oxybutynin vs. Venlafaxine

We are studying whether oxybutynin or venlafaxine is more effective in reducing hot flashes in women using endocrine therapy after breast cancer. We will also look at side effects and personal preferences between the two treatments.

Estrogen Receptor Positive Breast Cancer3-6 monthsConfirmation phase (III)No PlaceboStandard MedicinesEndocrinologyOncology

Methylphenidate for Cancer-Related Fatigue in Young Brain Tumor Survivors

We are studying whether methylphenidate can help reduce fatigue in patients who were treated for brain tumors during childhood or adolescence. Additionally, we will look at its effects on sleep, cognitive function, and quality of life.

Cancer-related Fatigue after Pediatric Brain Tumor Treatment3-6 monthsConfirmation phase (III)6-10 visitsStandard MedicinesCost ReimbursementOncologyPediatrics

Postmenopausal Bone Health: Everolimus and Exercise Study

We are investigating whether everolimus, exercise, or both can improve bone formation in healthy postmenopausal women. This study aims to help prevent bone loss and support skeletal health.

Healthy Participants3-6 monthsEfficacy phase (II)No PlaceboStandard MedicinesEndocrinologyInternal MedicineOrthopedics and Traumatology

Crohn's Disease: Vedolizumab vs. Adalimumab Dose Increase

We are studying whether Vedolizumab is more effective than increasing the dose of Adalimumab for Crohn's disease patients who are not responding well to their current treatment. This trial will help us understand which strategy leads to better remission and fewer side effects.

Crohn's Disease3-6 monthsMonitoring phase (IV)Post-Trial Drug AccessNo PlaceboStandard MedicinesGastroenterologyInternal Medicine

Uveal Melanoma: New Liver Treatment with Ipilimumab and Nivolumab

We are testing a new liver treatment combined with two immunotherapy drugs for patients with uveal melanoma that has spread to the liver. This study aims to see if the new approach improves survival without disease progression compared to standard treatment.

Uveal Melanoma with Liver Metastases3-6 monthsConfirmation phase (III)No PlaceboInvestigational MedicinesHepatologyOncology

Chronic Inflammatory Bowel Disease: Intravenous Lidocaine Study

We are investigating whether intravenous lidocaine can reduce abdominal pain in patients with chronic inflammatory bowel disease. Additionally, we will study how this treatment affects brain activity compared to healthy volunteers.

Inflammatory Bowel Disease3-6 monthsEfficacy phase (II)6-10 visitsNo PlaceboStandard MedicinesGastroenterologyInternal Medicine

Gastrointestinal Tolerability: Tegomil vs. Dimethyl Fumarate

We are comparing how well healthy volunteers tolerate two oral medications for gastrointestinal side effects. This study aims to understand which option may be easier on the stomach.

Multiple Sclerosis3-6 monthsSafety phase (I)Neurology

Coronary Artery Disease: Comparing Diabetes Medications

We are studying how well a new diabetes medication works to improve heart health in people with coronary artery disease and prediabetes. This trial compares a GLP-1 agonist and an SGLT-2 inhibitor to standard treatment.

Coronary Artery DiseasePrediabetesCoronary Atherosclerosis3-6 monthsMonitoring phase (IV)No PlaceboStandard MedicinesCardiologyEndocrinology

Preventing Blood Clots: REGN9933 and REGN7508 Study

We are studying two new medications to see if they can help prevent blood clots in adults with a peripherally inserted central catheter. The trial will also assess how safe these treatments are.

Venous Thromboembolism3-6 monthsEfficacy phase (II)6-10 visitsInvestigational MedicinesCost ReimbursementPartially RemoteCardiologyHematology