Search Clinical Trials in the European Union

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2381-2400 of 3,900 trials

Frozen Embryo Transfer: The Role of Corpus Luteum

We are studying how the presence of the corpus luteum affects pregnancies from frozen embryo transfers. This research may help us understand its impact on maternal and fetal health.

Infertility6-12 monthsMonitoring phase (IV)11-15 visitsNo PlaceboStandard MedicinesGynecology and Obstetrics

Pulmonary Arterial Hypertension: LTP001 Treatment Study

We are studying a new treatment called LTP001 in healthy adults and in individuals with pulmonary arterial hypertension. The goal is to evaluate its safety and how well it may improve exercise capacity and overall health.

Pulmonary Arterial HypertensionSafety phase (I)Efficacy phase (II)16-20 visitsPost-Trial Drug AccessInvestigational MedicinesCost ReimbursementPartially RemoteCardiologyPulmonology

Myomectomy: Misoprostol for Reducing Blood Loss

We are studying whether misoprostol can help reduce blood loss during myomectomy surgeries. This trial involves comparing its effects against a placebo in patients undergoing different surgical techniques.

Uterine FibroidsEfficacy phase (II)Standard MedicinesGynecology and Obstetrics

Ataxia Telangiectasia: EryDex Safety Study

We are assessing the safety and tolerability of EryDex in individuals with Ataxia Telangiectasia. Additionally, we’re exploring its potential effects on neurological symptoms.

Ataxia Telangiectasia (A-T)1-2 yearsConfirmation phase (III)Post-Trial Drug AccessNo PlaceboStandard MedicinesPartially RemoteInternal MedicineNeurology

Advanced Lung Cancer: Eftilagimod Alfa with Pembrolizumab

We are studying a new drug, eftilagimod alfa, combined with pembrolizumab and chemotherapy for patients with advanced non-small cell lung cancer. The goal is to see if this combination works better than standard treatments.

Advanced Non-Small Cell Lung Cancer>2 yearsConfirmation phase (III)Investigational MedicinesCost ReimbursementPartially RemoteOncology

Advanced Solid Tumors: MCLA-158 (Petosemtamab) Study

We are testing a new treatment called MCLA-158 for people with advanced solid tumors to see how well it works and how safe it is. This study looks at its effects alone and in combination with other therapies.

Metastatic Colorectal CancerMalignant Solid TumorSafety phase (I)Efficacy phase (II)Post-Trial Drug AccessNo PlaceboStandard MedicinesOncology

Skin Cancer Treatment: Nivolumab and Relatlimab Study

We are studying the effects of Nivolumab alone and in combination with Relatlimab for patients with advanced squamous cell carcinoma of the skin. This trial aims to find out which treatment may help control the disease better.

Locally Advanced/Metastatic Squamous Cell Carcinoma of the Skin>2 yearsEfficacy phase (II)No PlaceboStandard MedicinesDermatologyOncology

Glioblastoma: Radioimmunotherapy with Lutetium 177

We are investigating a new treatment using a targeted antibody for patients with glioblastoma. The study aims to determine the right dose and assess its safety and effectiveness.

Glioblastoma1-2 yearsSafety phase (I)NeurologyOncology

Retinitis Pigmentosa: Stem Cell Eye Treatment

We are testing a new stem cell-based treatment for people with retinitis pigmentosa to see if it is safe and tolerable. The study also aims to evaluate its potential to improve vision.

Retinitis Pigmentosa1-2 yearsSafety phase (I)Efficacy phase (II)No PlaceboInvestigational MedicinesOphthalmology

Advanced Solid Tumors: GSK5764227 Study

We are testing a new drug, GSK5764227, in people with advanced solid tumors to see how safe it is and how it affects their condition. This study aims to gather important information for future treatments.

Neoplasms1-2 yearsSafety phase (I)Oncology

Stroke Prevention: Low Dose Colchicine Study

We are investigating whether low dose colchicine can help prevent future strokes and other major vascular events in patients with a history of stroke due to atherosclerosis.

Cardiovascular Diseases>2 yearsConfirmation phase (III)6-10 visitsNo PlaceboStandard MedicinesCardiologyInternal Medicine

Palmo-Plantars Warts: HPV Vaccine Study

We are testing a nonavalent HPV vaccine to see if it helps people with difficult-to-treat warts on their hands and feet. The study aims to improve wart clearance, pain, and overall quality of life.

HPV Vaccine>2 yearsConfirmation phase (III)≤5 visitsStandard MedicinesPartially RemoteDermatologyInfectious Diseases

Obesity: PF-07976016 Medication Study

We are testing a new medication called PF-07976016 to see if it helps adults with obesity lose weight more effectively than a placebo. The study also looks at the safety of this medication for those already taking liraglutide.

ObesityOverweight6-12 monthsEfficacy phase (II)6-10 visitsInvestigational MedicinesPartially RemoteDiabetologyEndocrinology

Idiopathic Inflammatory Myopathies: Upadacitinib Study

We are testing whether Upadacitinib can help patients with idiopathic inflammatory myopathies maintain stable disease after stopping IVIG treatment. The study compares its effects to a placebo over 16 weeks.

PolymyositisDermatomyositisAntisynthetase Syndrome3-6 monthsEfficacy phase (II)6-10 visitsStandard MedicinesDermatologyRheumatology

Lung Cancer Treatment: Nivolumab + Relatlimab with Chemotherapy

We are studying if a new combination treatment helps people with advanced non-small cell lung cancer live longer compared to standard treatment. This trial is for those whose cancer has spread or returned after previous treatment.

Advanced Non-Small Cell Lung Cancer>2 yearsConfirmation phase (III)Post-Trial Drug AccessNo PlaceboInvestigational MedicinesCost ReimbursementOncology

Osteoarthritis Behind the Kneecap: Nasal Cartilage Implantation

We are studying a new nasal cartilage treatment for people with osteoarthritis behind the kneecap to see if it improves recovery compared to standard care. The trial will also assess safety and how well the treatment works over time.

Knee OsteoarthritisPatellofemoral Osteoarthritis>2 yearsEfficacy phase (II)6-10 visitsNo PlaceboInvestigational MedicinesInternal MedicineOrthopedics and Traumatology

Advanced Solid Tumors: Anti-GD2 ADC M3554

We are testing a new treatment for patients with advanced solid tumors to see if it can improve their condition. This study aims to evaluate the safety and effectiveness of the drug.

Soft Tissue SarcomaGlioblastomaAdvanced Solid Tumors1-2 yearsSafety phase (I)Oncology

Postoperative Pain Relief: PENG Block for Hip Surgery

We are studying whether a nerve block can reduce pain after hip surgery called peri-acetabular osteotomy. This trial compares the nerve block to a placebo to see if it helps patients feel better and use fewer pain medications.

Periacetabular Osteotomy1-2 yearsMonitoring phase (IV)Standard MedicinesOrthopedics and TraumatologyOtolaryngology

Advanced Solid Tumors: Saruparib Study

We are investigating how the drug saruparib works and its safety in adults with advanced solid tumors. This trial aims to provide insights into its potential benefits for patients.

Advanced Solid Tumors1-2 yearsSafety phase (I)Oncology

Heart Attack Recovery: Bempedoic Acid Study

We are investigating whether adding bempedoic acid to standard cholesterol medications helps heart attack patients reach their cholesterol goals. This study aims to improve treatment for those not meeting guidelines with current therapies.

Heart Attack1-2 yearsConfirmation phase (III)≤5 visitsNo PlaceboStandard MedicinesCardiologyInternal Medicine