Search Clinical Trials in the European Union

Duration
Visits
Phase
Intake methods
Benefits
Drugs
Locations
Clinical Specialty
2981-3000 of 3,900 trials

Wrist Osteoarthritis: Microfat and PRP Injection Study

We are testing whether injections of your own fat and platelet-rich plasma can help relieve pain in wrist osteoarthritis compared to standard surgery. This study aims to see if the new treatment is just as effective and safe.

Wrist Osteoarthritis>2 yearsEfficacy phase (II)≤5 visitsNo PlaceboInvestigational MedicinesOrthopedics and TraumatologyRheumatology

Acute Demyelinating Syndromes in Children: Azathioprine vs. Rituximab

We are studying whether starting treatment immediately with azathioprine or rituximab helps children with anti-MOG antibodies better than delaying treatment until a second attack. The goal is to see which method reduces relapses and improves health outcomes.

Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD)>2 yearsConfirmation phase (III)11-15 visitsPost-Trial Drug AccessNo PlaceboStandard MedicinesCost ReimbursementPartially RemoteNeurologyRheumatology

Hereditary Angioedema: Deucrictibant Tablet Study

We are evaluating a new oral medication to prevent angioedema attacks in adolescents and adults with hereditary angioedema. The study aims to determine its effectiveness and safety compared to a placebo.

Hereditary Angioedema3-6 monthsConfirmation phase (III)Post-Trial Drug AccessInvestigational MedicinesCost ReimbursementPartially RemoteAllergologyInternal Medicine

Hereditary Angioedema: Deucrictibant Extended-Release Tablet

We are studying a new oral medication to prevent angioedema attacks in adolescents and adults with hereditary angioedema. The trial will evaluate its safety, effectiveness, and impact on quality of life.

Hereditary Angioedema>2 yearsConfirmation phase (III)Post-Trial Drug AccessNo PlaceboInvestigational MedicinesCost ReimbursementPartially RemoteAllergologyInternal Medicine

Iron Deficiency Anemia in Children: Ferumoxytol Study

We are testing the safety and effectiveness of the drug ferumoxytol for children with iron deficiency anemia. This study compares it to an existing treatment to see how well it works.

Iron Deficiency Anemia≤3 monthsConfirmation phase (III)≤5 visitsNo PlaceboInvestigational MedicinesHematologyPediatrics

Caspofungin for ICU Yeast Infections

We are studying whether caspofungin can help patients in the ICU with yeast infections in the abdomen. The trial compares this treatment to a placebo to see if it improves recovery and reduces mortality.

Yeast Intra-Abdominal Infection (Peritonitis)>2 yearsConfirmation phase (III)6-10 visitsInvestigational MedicinesInfectious DiseasesInternal Medicine

Kidney Biopsy: Desmopressin Safety Study

We are studying whether Desmopressin can help prevent bleeding during kidney biopsies. This trial looks at its effects on safety and recovery time for patients.

Glomerulonephritis>2 yearsConfirmation phase (III)Standard MedicinesInternal MedicineNephrology

Metastatic Thyroid Cancer: Personalized 131I Therapy

We are studying if a personalized approach to administering radioactive iodine can improve treatment outcomes for patients with metastatic thyroid cancer. This trial also looks at how genetic factors may affect treatment effectiveness.

Thyroid Cancer>2 yearsEfficacy phase (II)Standard MedicinesOncology

Fertility Preservation for Breast Cancer: Tamoxifen and Ovarian Stimulation

We are studying whether combining Tamoxifen with ovarian stimulation can help women with breast cancer collect healthy eggs before chemotherapy. This may support their chances of having children in the future.

Breast CancerEfficacy phase (II)No PlaceboStandard MedicinesGynecology and ObstetricsOncology

Ulcerative Colitis: Vixarelimab Study

We are testing Vixarelimab to see if it is safe and effective for people with moderate to severe active ulcerative colitis. This study aims to improve treatment options for this condition.

Ulcerative Colitis1-2 yearsSafety phase (I)GastroenterologyInternal Medicine

Liver Cirrhosis: RTX001 Macrophage Therapy

We are studying a new treatment using RTX001 autologous macrophages for people with decompensated liver cirrhosis. The trial aims to evaluate its safety and effectiveness in improving liver function.

Liver Cirrhosis>2 yearsSafety phase (I)Efficacy phase (II)6-10 visitsPost-Trial Drug AccessNo PlaceboInvestigational MedicinesPartially RemoteHepatologyInternal Medicine

Cancer Treatment: Decitabine and Cedazuridine

We are studying how safe and effective a combination of Decitabine and Cedazuridine is for cancer patients with kidney problems. This research aims to improve treatment options for those affected.

Acute Myeloid Leukemia (AML)Myelodysplastic Syndrome (MDS)Solid Tumors>2 yearsSafety phase (I)NephrologyOncology

Sjögren’s Disease: Sibeprenlimab Treatment Study

We are investigating whether Sibeprenlimab can improve symptoms in people with Sjögren’s Disease compared to a placebo. The study will also look at the safety and tolerability of this new treatment.

Sjögren's Disease1-2 yearsEfficacy phase (II)11-15 visitsPost-Trial Drug AccessInvestigational MedicinesCost ReimbursementInfectious DiseasesRheumatology

Lung Fibrosis in Systemic Rheumatic Diseases: Imaging Study

We are investigating whether advanced imaging can help identify early signs of lung fibrosis in patients with systemic rheumatic diseases. This may help us understand lung function changes and improve patient care.

Connective Tissue Disease with Risk of Lung Disease1-2 yearsEfficacy phase (II)≤5 visitsNo PlaceboInvestigational MedicinesPulmonologyRheumatology

Oxytocin for Children with Autism and Intellectual Disabilities

We are studying whether oxytocin can safely support educational measures for children aged 6 to 12 with autism and intellectual disabilities. This trial will help us understand its feasibility and safety in managing challenging behaviors.

Autism Spectrum Disorder and Intellectual Disability>2 yearsEfficacy phase (II)Confirmation phase (III)Standard MedicinesPediatricsPsychiatry

Metastatic Colorectal Cancer: Nivolumab and Ipilimumab Study

We are testing a combination of two immunotherapy drugs for patients with metastatic colorectal cancer that is resistant to previous treatments. This study aims to find out if this combination can improve outcomes for these patients.

Metastatic Colorectal Cancer>2 yearsEfficacy phase (II)Oncology

Prucalopride for Refractory Gastro-Esophageal Reflux Disease

We are testing a new medication for patients with GERD who still have symptoms despite taking standard treatments. The goal is to see if this drug can improve their reflux symptoms.

Gastro-esophageal Reflux Disease (GERD)≤3 monthsMonitoring phase (IV)≤5 visitsPost-Trial Drug AccessStandard MedicinesCost ReimbursementPartially RemoteGastroenterologyInternal Medicine

HER2 Positive Esophageal Cancer: HERES Trial

We are studying whether adding trastuzumab to standard chemotherapy and immunotherapy helps patients with HER2 positive esophageal squamous cell carcinoma live longer without disease progression.

Esophageal Cancer>2 yearsEfficacy phase (II)6-10 visitsNo PlaceboStandard MedicinesOncology

Bladder Cancer Treatment: BCG vs. BCG/EMDA-MMC

We are studying two treatment methods for high-risk non-muscle-invasive bladder cancer to see which is more effective and safer. This trial will help us understand the best approach to prevent disease progression.

Bladder Cancer6-12 monthsConfirmation phase (III)No PlaceboStandard MedicinesGynecology and ObstetricsInternal MedicineUrology

Type 3 Spinal Muscular Atrophy: NMD670 Study

We are testing the safety and effectiveness of NMD670 in adults with Type 3 spinal muscular atrophy. The study aims to see if it improves muscle strength and function compared to a placebo.

Spinal Muscular Atrophy Type III3-6 monthsEfficacy phase (II)6-10 visitsInvestigational MedicinesCost ReimbursementNeurologyOrthopedics and Traumatology