Search Clinical Trials in the European Union

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2961-2980 of 3,900 trials

Neuroendocrine Neoplasms: Advanced PET/CT Imaging Study

We are exploring how combined PET/CT scans can help predict survival outcomes for patients with neuroendocrine neoplasms. This study may also identify who is eligible for targeted therapies based on imaging results.

Neuroendocrine Carcinoma1-2 yearsEfficacy phase (II)No PlaceboInvestigational MedicinesEndocrinologyOncology

Advanced Breast Cancer: Inavolisib Treatment Study

We are studying a new treatment combining inavolisib with standard medications for patients with advanced hormone receptor-positive breast cancer. The goal is to see if this combination works better than a placebo in managing the disease.

Advanced Breast Cancer>2 yearsConfirmation phase (III)6-10 visitsPost-Trial Drug AccessInvestigational MedicinesPartially RemoteOncology

Immune Thrombocytopenia: Rituximab with Belimumab

We are studying whether adding belimumab to rituximab helps adults with persistent immune thrombocytopenia. This trial will compare the effects of the combination treatment to rituximab alone.

Immune Thrombocytopenia>2 yearsConfirmation phase (III)6-10 visitsStandard MedicinesHematology

Recurrent Brain Tumors in Children: Ultrasound Blood-Brain Barrier Study

We are evaluating a new ultrasound device to safely open the blood-brain barrier before chemotherapy in children with recurrent brain tumors. This study aims to see how well this method works and its effects on tumor progression.

Glioblastoma>2 yearsSafety phase (I)Efficacy phase (II)No PlaceboStandard MedicinesNeurologyOncologyPediatrics

COPD Management: Azithromycin Based on Mucus Properties

We are studying whether prescribing azithromycin based on mucus rheology helps reduce COPD flare-ups compared to standard treatment. This trial aims to improve care for patients with chronic airway disease.

Chronic Obstructive Pulmonary Disease>2 yearsEfficacy phase (II)No PlaceboStandard MedicinesInternal MedicinePulmonology

Early Breast Cancer: Trastuzumab-Deruxtecan vs. Standard Care

We are studying a new treatment for early breast cancer patients who have had a molecular relapse. The trial aims to see if this new therapy clears cancer markers more effectively than standard treatments.

HER2-positive Breast CancerBreast Cancer>2 yearsConfirmation phase (III)Post-Trial Drug AccessNo PlaceboInvestigational MedicinesOncology

Metastatic Colorectal Cancer: S 95005 with Bevacizumab

We are studying a new treatment combination for patients with metastatic colorectal cancer who cannot receive intensive therapy. The goal is to see if it helps patients live longer without disease progression compared to standard treatment.

Metastatic Colorectal Cancer1-2 yearsConfirmation phase (III)No PlaceboStandard MedicinesPartially RemoteOncology

B-Cell Lymphoma: Valemetostat Tosylate Study

We are testing a new treatment for patients with relapsed or refractory B-cell lymphoma. The study aims to see how well it works and its safety across different lymphoma types.

Relapse/Refractory B-Cell Lymphoma>2 yearsEfficacy phase (II)No PlaceboInvestigational MedicinesCost ReimbursementHematologyOncology

Stroke Prevention: ASPIRING Study

We are investigating if an oral antiplatelet drug can help prevent serious heart and brain events in stroke survivors. This study compares the effects of this medication to standard care without antiplatelet drugs.

Intracerebral Hemorrhage>2 yearsMonitoring phase (IV)No PlaceboStandard MedicinesCost ReimbursementPartially RemoteCardiologyInternal MedicineNeurology

Liver Transplant: QEL-001 Treatment Study

We are testing a new CAR T cell therapy for patients who received an HLA-A2 mismatched liver transplant. The goal is to evaluate its safety and how well it works in this specific group.

Liver Transplant Rejection3-6 monthsSafety phase (I)Efficacy phase (II)No PlaceboInvestigational MedicinesCost ReimbursementHepatologyInternal Medicine

High-Risk Breast Cancer: Personalized Chemotherapy Study

We are investigating a new chemotherapy treatment for patients with high-risk, HER2-negative breast cancer to see if it improves survival rates compared to standard therapies. This trial is for individuals with specific genetic profiles, including those without known BRCA mutations.

Breast Cancer>2 yearsConfirmation phase (III)No PlaceboStandard MedicinesOncology

Gastroparesis: Naronapride Study

We are evaluating a new medication for people with moderate gastroparesis to see how it works and its safety compared to healthy individuals. This study aims to improve treatment options for those affected by this condition.

GastroparesisSafety phase (I)Gastroenterology

Intensive Care: INCEPT Trial

We are studying different treatments for adults admitted to the intensive care unit to see how they affect recovery. This trial aims to improve care by understanding the best practices among clinicians.

Intensive Care>2 yearsMonitoring phase (IV)No PlaceboStandard MedicinesCardiologyInfectious DiseasesInternal MedicineNeurologyPulmonology

Glioblastoma Multiforme: Long-Term Safety of Temferon

We are monitoring the long-term safety and effects of Temferon in patients who have been treated for glioblastoma multiforme. This study aims to understand any potential side effects and how the disease may progress.

Glioblastoma MultiformeSafety phase (I)Efficacy phase (II)No PlaceboInvestigational MedicinesPartially RemoteNeurologyOncology

Psoriatic Arthritis: Sonelokimab Treatment Study

We are investigating whether sonelokimab can effectively reduce symptoms in adults with active psoriatic arthritis who have not yet tried biologic treatments. The study will also assess the safety of this new medication compared to a placebo.

Psoriatic Arthritis1-2 yearsConfirmation phase (III)16-20 visitsPost-Trial Drug AccessInvestigational MedicinesCost ReimbursementDermatologyRheumatology

Psoriatic Arthritis: Sonelokimab Study

We are investigating the effects of sonelokimab in adults with active psoriatic arthritis who haven't responded to other treatments. This study compares sonelokimab to a placebo and an existing medication to see how well it works.

Psoriatic Arthritis1-2 yearsConfirmation phase (III)Post-Trial Drug AccessInvestigational MedicinesCost ReimbursementDermatologyRheumatology

Colorectal Cancer: Dendritic Cell Vaccine Study

We are testing a personalized vaccine made from patients' own cells after surgery for stage IV colorectal cancer. The goal is to see if it safely boosts the immune response against cancer.

Stage IV Colorectal Cancer>2 yearsEfficacy phase (II)6-10 visitsNo PlaceboInvestigational MedicinesOncology

Pancreatic Cancer: Sotorasib with Chemotherapy

We are studying the safety of combining sotorasib with standard chemotherapy for patients with advanced pancreatic cancer that has a specific genetic mutation. This trial aims to see if this combination improves treatment outcomes.

Pancreatic Cancer≤3 monthsSafety phase (I)No PlaceboStandard MedicinesGastroenterologyOncology

B-Cell Malignancies: BGB-16673 Treatment Study

We are investigating the safety and effectiveness of BGB-16673 combined with other treatments for patients with relapsed or refractory B-cell malignancies. This study aims to find the best dose and assess how well the treatment works.

Relapsed or Refractory B-Cell Malignancies>2 yearsSafety phase (I)Efficacy phase (II)Post-Trial Drug AccessNo PlaceboInvestigational MedicinesPartially RemoteOncology

Cryoglobulinemia Vasculitis: Belimumab Study

We are studying whether belimumab can help people with non-infectious active cryoglobulinemia vasculitis compared to a placebo. The goal is to see if it improves symptoms and overall health.

Cryoglobulinemia Vasculitis6-12 monthsEfficacy phase (II)≤5 visitsStandard MedicinesCost ReimbursementInfectious DiseasesRheumatology