Search Clinical Trials in the European Union

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3201-3220 of 3,900 trials

Knee Osteoarthritis: KBP-336 Medication Study

We are testing a new medication for obese individuals with knee osteoarthritis to see if it helps reduce weight and pain. The study will also look at other symptoms and overall safety compared to a placebo.

Knee OsteoarthritisObesity6-12 monthsEfficacy phase (II)11-15 visitsInvestigational MedicinesPartially RemoteInternal MedicineOrthopedics and Traumatology

BOTOX® for Preventing Pancreatic Fistula After Surgery

We are studying whether BOTOX® injections before surgery can help prevent complications in patients undergoing distal pancreatectomy. This trial will assess the safety and effectiveness of this approach.

Postoperative Pancreatic Fistulas≤3 monthsSafety phase (I)Efficacy phase (II)Post-Trial Drug AccessNo PlaceboStandard MedicinesCost ReimbursementPartially RemoteGastroenterologyInternal Medicine

Retinoblastoma: New Conservative Treatment Approaches

We are studying different chemotherapy and local treatment methods for children with retinoblastoma to see if they can preserve vision without using radiation. This trial includes various patient groups based on their specific conditions.

RetinoblastomaEfficacy phase (II)No PlaceboStandard MedicinesOncologyOphthalmology

T-Guard for Early Diffuse Cutaneous Systemic Sclerosis

We are studying the safety and effectiveness of T-Guard in patients with early diffuse cutaneous systemic sclerosis. This trial will help us understand how well the treatment works and how it is processed in the body.

Diffuse Systemic Sclerosis1-2 yearsSafety phase (I)Efficacy phase (II)No PlaceboInvestigational MedicinesCost ReimbursementDermatologyInternal MedicineRheumatology

Psoriatic Arthritis: JNJ-77242113 Study

We are testing a new medication for people with active psoriatic arthritis who have used other biologic treatments. The study aims to see if it can reduce symptoms better than a placebo.

Psoriatic Arthritis1-2 yearsConfirmation phase (III)11-15 visitsInvestigational MedicinesCost ReimbursementPartially RemoteDermatologyRheumatology

Lymphoma: Comparing Pneumococcal Vaccines

We are studying the effectiveness of two pneumococcal vaccines in adults with lymphoma receiving chemotherapy. This trial aims to see which vaccination strategy provides a better immune response and is safer.

Lymphoma>2 yearsMonitoring phase (IV)No PlaceboStandard MedicinesInfectious DiseasesOncology

Hydrocortisone Absorption: Oral vs. Oral Mucosa

We are comparing how well hydrocortisone is absorbed from dissolvable films in healthy volunteers and adults with adrenal insufficiency. This study aims to find the most effective way to deliver this important medication.

Adrenal Insufficiency1-2 yearsSafety phase (I)Endocrinology

IVF/ICSI: Optimizing Recombinant FSH Dosing

We are studying the best dose of recombinant FSH for patients undergoing IVF/ICSI to improve hormone levels and pregnancy outcomes. This research may help enhance fertility treatment success.

Female Subfertility1-2 yearsMonitoring phase (IV)No PlaceboInvestigational MedicinesEndocrinologyGynecology and Obstetrics

Lung Cancer Treatment: Immunotherapy and Radiation

We are studying a new treatment combining immunotherapy and radiation for elderly or unfit patients with advanced lung cancer. The aim is to see if this approach improves survival and quality of life.

Unresectable Stage III Non-Small Cell Lung Cancer3-6 monthsEfficacy phase (II)No PlaceboStandard MedicinesOncology

EGFR-Mutant Non-Small Cell Lung Cancer: BG-60366 Study

We are investigating a new treatment for patients with EGFR-mutant non-small cell lung cancer. The study will help us understand its safety and how well it works against the cancer.

EGFR-Mutant Non-Small Cell Lung Cancer>2 yearsSafety phase (I)Oncology

Myeloma Treatment: Elranatamab vs. Daratumumab

We are studying whether elranatamab combined with lenalidomide helps patients with newly diagnosed myeloma maintain remission better than daratumumab with lenalidomide after a transplant. This trial will also assess safety and quality of life.

Multiple Myeloma>2 yearsEfficacy phase (II)No PlaceboStandard MedicinesCost ReimbursementHematologyOncology

Advanced Liver Cancer: CS1003 with Lenvatinib

We are studying a new treatment combined with lenvatinib for people with advanced liver cancer. The trial compares this combination to a placebo with lenvatinib to see which is more effective and safe.

Unresectable Advanced Liver Cancer>2 yearsConfirmation phase (III)Post-Trial Drug AccessInvestigational MedicinesPartially RemoteHepatologyOncology

TOASST Study: Comparing Steroid Withdrawal Methods

We are studying whether stopping glucocorticoids suddenly is as safe as tapering them for patients with inflammatory disorders. This research may help improve treatment strategies and patient outcomes.

Inflammatory or Autoimmune Disorders>2 yearsMonitoring phase (IV)6-10 visitsStandard MedicinesCost ReimbursementPartially RemoteInternal MedicineRheumatology

Bladder Cancer: V940 and BCG Combination Study

We are investigating whether a new treatment, V940, combined with BCG can improve outcomes for people with high-risk non-muscle invasive bladder cancer compared to BCG alone. This study will also assess the safety of all treatment options.

Bladder Cancer>2 yearsEfficacy phase (II)No PlaceboInvestigational MedicinesPartially RemoteOncology

Statin Therapy for Frail Older Adults After Stroke

We are studying whether starting statin medication helps frail individuals aged 70 and older who have had a recent stroke or transient ischemic attack. The goal is to see if it improves heart health and quality of life.

Ischemic Stroke and Transient Ischemic Attack>2 yearsMonitoring phase (IV)6-10 visitsStandard MedicinesPartially RemoteCardiologyInternal MedicineNeurology

Rheumatoid Arthritis: CIT-013 Study

We are investigating a new medication, CIT-013, for people with moderately active rheumatoid arthritis. The study aims to see if it helps reduce disease activity and to understand its safety.

Moderately Active Rheumatoid Arthritis3-6 monthsEfficacy phase (II)11-15 visitsNo PlaceboInvestigational MedicinesCost ReimbursementPartially RemoteRheumatology

COVID-19 Vaccine Immunology Study in Finland

We are studying how different COVID-19 vaccines affect immune responses in various groups. This research may help us understand the need for boosters and how well vaccines work against different virus variants.

COVID-196-12 monthsMonitoring phase (IV)No PlaceboInvestigational MedicinesInfectious DiseasesInternal Medicine

Pancreatic Cancer: Hyperpolarized Pyruvate Imaging Study

We are testing a new imaging technique using hyperpolarized pyruvate in patients with pancreatic cancer. This study aims to confirm its safety and gather data to help improve future treatments.

Pancreatic Cancer>2 yearsEfficacy phase (II)≤5 visitsNo PlaceboInvestigational MedicinesOncologyOtolaryngology

Ovarian Cancer: Olaparib and Bevacizumab Study

We are studying how well a new test identifies genetic markers in patients with advanced ovarian cancer and whether combining Olaparib with Bevacizumab improves treatment outcomes. This trial aims to evaluate the safety and effectiveness of this drug combination.

Advanced Ovarian, Fallopian Tube, or Peritoneal Cancer6-12 monthsEfficacy phase (II)16-20 visitsNo PlaceboStandard MedicinesGynecology and ObstetricsOncology

Multiple Myeloma: New Treatment Combinations

We are studying a combination of new medications for people with newly diagnosed multiple myeloma who can undergo a transplant. The goal is to evaluate their safety and effectiveness in improving treatment outcomes.

Multiple MyelomaEfficacy phase (II)No PlaceboInvestigational MedicinesPartially RemoteHematologyOncology