Search Clinical Trials in the European Union

Duration
Visits
Phase
Intake methods
Benefits
Drugs
Locations
Clinical Specialty
3701-3720 of 3,900 trials

Acute Myeloid Leukemia: Bleximenib, Venetoclax, and Azacitidine Study

We are studying a combination of three medications for people with newly diagnosed acute myeloid leukemia who cannot receive intensive chemotherapy. The aim is to see if this combination works better than the standard treatment alone.

Acute Myeloid LeukemiaConfirmation phase (III)Investigational MedicinesPartially RemoteHematologyOncology

Prostate Cancer: JSB462 and Lutetium Combination Study

We are studying a new treatment combining JSB462 with lutetium for adult men with advanced prostate cancer. The goal is to see how well this combination works and its safety compared to standard treatment.

Metastatic Castration-Resistant Prostate Cancer6-12 monthsEfficacy phase (II)11-15 visitsNo PlaceboInvestigational MedicinesOncologyUrology

Ravulizumab for Pediatric IgA Nephropathy

We are studying how Ravulizumab works in children with Primary Immunoglobulin A Nephropathy. This research may help us understand its effects and safety in younger patients.

Immunoglobulin A Nephropathy6-12 monthsConfirmation phase (III)>20 visitsPost-Trial Drug AccessNo PlaceboStandard MedicinesNephrologyPediatrics

Refractory Epilepsy: YCJ-01 Cannabis Extract

We are studying a cannabis extract to see if it can help reduce seizures in patients with difficult-to-control epilepsy due to Tuberous Sclerosis Complex. The trial will also assess the safety of this treatment.

Tuberous Sclerosis ComplexRefractory Epilepsy in Tuberous Sclerosis Complex6-12 monthsConfirmation phase (III)6-10 visitsPost-Trial Drug AccessInvestigational MedicinesCost ReimbursementPartially RemoteNeurologyPediatrics

Ovarian Cancer: Sentinel Lymph Node Technique Study

We are evaluating a new technique to detect lymph node spread in early-stage ovarian cancer patients. This study aims to see how well it works compared to traditional methods.

Ovarian Cancer>2 yearsConfirmation phase (III)No PlaceboStandard MedicinesGynecology and ObstetricsOncology

Breast Cancer Treatment: Sac-TMT vs. Standard Chemotherapy

We are studying a new treatment for high-risk early-stage breast cancer to see if it works better than standard chemotherapy combined with pembrolizumab. This trial is for individuals with triple-negative or hormone receptor-low positive breast cancer.

Triple Negative Breast Cancer1-2 yearsConfirmation phase (III)No PlaceboInvestigational MedicinesCost ReimbursementOncology

Bipolar-I Disorder: KarXT Treatment Study

We are testing a new treatment called KarXT for people experiencing manic episodes in Bipolar-I Disorder. The study aims to see if it helps reduce mania symptoms better than a placebo.

Bipolar Disorder with Mania≤3 monthsConfirmation phase (III)Post-Trial Drug AccessInvestigational MedicinesPsychiatry

Rheumatoid Arthritis: Study of PIT565

We are testing a new treatment called PIT565 for individuals with rheumatoid arthritis. The study aims to understand its safety and how the body processes it.

Rheumatoid Arthritis>2 yearsSafety phase (I)Rheumatology

Ulcerative Colitis: Testing OD-07656

We are studying a new treatment called OD-07656 for people with moderately to severely active ulcerative colitis. The trial aims to evaluate its safety and effectiveness compared to another therapy.

Ulcerative ColitisEfficacy phase (II)No PlaceboInvestigational MedicinesGastroenterologyInternal Medicine

Intestinal Failure-Associated Liver Disease: NST-6179 Study

We are testing a new oral medication, NST-6179, for individuals with Intestinal Failure-Associated Liver Disease. The study aims to understand its safety and how it affects liver health.

Intestinal Failure-Associated Liver Disease3-6 monthsEfficacy phase (II)6-10 visitsInvestigational MedicinesPartially RemoteGastroenterologyHepatology

WVE-007 for Adults with Overweight or Obesity

We are testing a new treatment called WVE-007 to see how it affects adults living with overweight or obesity. This study aims to understand its safety and how it may help with weight management.

Overweight and Obesity in Adults1-2 yearsSafety phase (I)EndocrinologyInternal Medicine

Knee Replacement Surgery: Local Anesthetic Comparison

We are studying whether using 20 mL of local anesthetic instead of 10 mL during a nerve block can reduce opioid use and improve pain management after knee surgery.

Postoperative Pain After Knee Surgery≤3 monthsMonitoring phase (IV)No PlaceboStandard MedicinesInternal MedicineOrthopedics and TraumatologyOtolaryngology

Ulcerative Colitis: Mirikizumab with Tirzepatide

We are studying whether combining mirikizumab with tirzepatide helps adults with moderately to severely active ulcerative colitis and obesity achieve better remission and weight loss than mirikizumab alone.

Obesity or OverweightUlcerative Colitis1-2 yearsConfirmation phase (III)16-20 visitsStandard MedicinesPartially RemoteEndocrinologyGastroenterology

Crohn’s Disease: Mirikizumab with Tirzepatide

We are studying whether a combination of mirikizumab and tirzepatide helps adults with moderately to severely active Crohn’s disease achieve better remission and weight loss than mirikizumab alone.

Crohn’s DiseaseObesity or Overweight1-2 yearsConfirmation phase (III)16-20 visitsStandard MedicinesCost ReimbursementPartially RemoteEndocrinologyGastroenterology

Metastatic Esophagogastric Cancer: MT-302 with CapOx

We are investigating the safety and early effectiveness of a new treatment, MT-302, combined with CapOx chemotherapy for patients with metastatic esophagogastric cancer.

Metastatic Esophagogastric Cancer>2 yearsSafety phase (I)Efficacy phase (II)Oncology

MK-7228: A New Medication Study

We are investigating the effects of MK-7228 in healthy men to understand its safety and how it works. This research may help inform future treatments.

Atherosclerosis1-2 yearsSafety phase (I)CardiologyInternal Medicine

Cholangiocarcinoma: Ivosidenib Maintenance Therapy

We are studying whether the drug ivosidenib can help patients with mIDH1 cholangiocarcinoma after standard chemotherapy. The trial will also look at its safety and effects on quality of life.

Cholangiocarcinoma Treatment>2 yearsEfficacy phase (II)Confirmation phase (III)16-20 visitsNo PlaceboStandard MedicinesGastroenterologyOncology

Type 2 Diabetes: Insulin NNC0471-0119 via Pump

We are studying how a new insulin works in people with type 2 diabetes when delivered through an insulin pump. This research may help improve diabetes management.

Type 2 Diabetes6-12 monthsSafety phase (I)DiabetologyEndocrinology

Improving Sleep and Mood in Postmenopausal Women: DHEA and Melatonin Study

We are studying whether a combination of DHEA and melatonin can enhance sleep quality and mood in postmenopausal women. This research may help address sleep issues and mood changes related to menopause.

Menopause and Sleep Disorders≤3 monthsConfirmation phase (III)Standard MedicinesGynecology and ObstetricsInternal MedicinePsychiatry

TAILORED-PROM: Personalized Treatment for Preterm Premature Rupture of Membranes

We are studying if a customized antibiotic and steroid therapy can help prolong pregnancy and improve outcomes for mothers and newborns. This approach may reduce unnecessary antibiotic use compared to standard treatments.

Preterm Premature Rupture of Membranes>2 yearsConfirmation phase (III)No PlaceboStandard MedicinesPartially RemoteGynecology and ObstetricsInfectious Diseases