Search Clinical Trials in the European Union

3-6 months
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61-80 of 331 trials

DLBCL Treatment: Dexrazoxane for Heart Protection

We are studying whether dexrazoxane can help prevent heart problems in patients with diffuse large B-cell lymphoma receiving chemotherapy. This trial will also compare treatment responses and monitor any side effects.

Diffuse Large B-Cell Lymphoma3-6 monthsConfirmation phase (III)6-10 visitsNo PlaceboStandard MedicinesCardiologyOncology

Acute Myeloid Leukemia: Cobicistat with Venetoclax and Azacitidine

We are studying a new treatment combination for patients with acute myeloid leukemia who cannot receive intensive chemotherapy. This trial aims to see if adding cobicistat to venetoclax and azacitidine improves survival and treatment outcomes.

Acute Myeloid Leukaemia3-6 monthsEfficacy phase (II)Post-Trial Drug AccessNo PlaceboStandard MedicinesInternal MedicineOncology

Posaconazole for Young Children with Fungal Infections

We are studying how well Posaconazole works and its safety in children under 2 years old with invasive fungal infections. This research will help us understand its effects compared to older patients.

Fungal Infection3-6 monthsEfficacy phase (II)6-10 visitsNo PlaceboStandard MedicinesInfectious DiseasesPediatrics

Hypophosphatasia in Children: ALXN1850 Study

We are studying a new treatment, ALXN1850, for children with hypophosphatasia who haven't been treated before. The goal is to see if it improves bone health and quality of life compared to a placebo.

Hypophosphatasia3-6 monthsConfirmation phase (III)16-20 visitsPost-Trial Drug AccessInvestigational MedicinesCost ReimbursementPartially RemoteOrthopedics and TraumatologyPediatrics

Chronic Pain Prevention: Duloxetine for Hernia Surgery

We are studying whether duloxetine can help prevent chronic pain in patients at high risk after inguinal hernia repair. We will also compare its safety to a placebo.

Chronic Pain After Surgery3-6 monthsConfirmation phase (III)Investigational MedicinesPartially RemoteInternal MedicineNeurologyOrthopedics and Traumatology

Peptide Receptor Radionuclide Therapy: LA-SSA Study

We are investigating how a long-acting medication affects radiation doses in tumors and normal tissues during treatment for certain cancers. This may help improve the effectiveness and safety of future therapies.

Neuroendocrine Tumors (NETs)3-6 monthsMonitoring phase (IV)No PlaceboStandard MedicinesOncology

High-Risk Aggressive B-Cell Lymphomas: R-Hyper-CVAD/R-MA Treatment

We are studying a new treatment approach for patients with high-risk aggressive B-cell lymphomas to see if it is effective and safe. This trial aims to improve outcomes for those facing this serious condition.

Lymphoma3-6 monthsEfficacy phase (II)No PlaceboStandard MedicinesHematologyOncology

EPO-TRAUMA: Epoetin Alfa for Critically Ill Trauma Patients

We are studying whether epoetin alfa can lower the risk of death and severe disability in critically ill patients after trauma. This trial compares its effects to a placebo treatment.

Traumatic Injury3-6 monthsConfirmation phase (III)≤5 visitsStandard MedicinesInternal MedicinePulmonology

Efgartigimod PH20 SC for Children with Generalized Myasthenia Gravis

We are studying a new treatment for children aged 2 to under 18 with generalized myasthenia gravis. The trial will help us understand the right dose and evaluate its safety and effects on daily life.

Myasthenia Gravis3-6 monthsEfficacy phase (II)Confirmation phase (III)≤5 visitsPost-Trial Drug AccessNo PlaceboStandard MedicinesCost ReimbursementPartially RemoteInternal MedicineNeurology

Methylphenidate for Children with KBG Syndrome

We are studying how well methylphenidate helps children and adolescents with KBG syndrome manage attention and emotional symptoms. This trial also looks at family functioning and any side effects compared to typical ADHD treatments.

KBG Syndrome3-6 monthsMonitoring phase (IV)6-10 visitsInvestigational MedicinesCost ReimbursementPartially RemotePediatricsPsychiatry

Recurrent Diverticulitis: MBK-01 Capsules

We are studying whether MBK-01, a new intestinal microbiota capsule, can help reduce episodes of recurrent diverticulitis. The trial will also assess its safety and find the best dosage for patients.

Acute Diverticulitis3-6 monthsEfficacy phase (II)6-10 visitsNo PlaceboInvestigational MedicinesGastroenterology

Cystectomy Complications: Antifungal Treatment Study

We are testing whether a new antifungal medication can help reduce complications after radical cystectomy. This study compares the medication to a placebo to see if it makes a difference.

Fungal Infection3-6 monthsMonitoring phase (IV)Standard MedicinesInfectious DiseasesUrology

Radiprodil for Seizures in Tuberous Sclerosis and Focal Cortical Dysplasia

We are studying the safety and effects of radiprodil on seizures and behavior in patients with Tuberous Sclerosis Complex or Focal Cortical Dysplasia Type II. This research may help improve treatment options for these conditions.

Focal Cortical Dysplasia (FCD)Tuberous Sclerosis Complex (TSC)3-6 monthsSafety phase (I)Efficacy phase (II)16-20 visitsNo PlaceboInvestigational MedicinesPartially RemoteNeurology

Preventing Diabetes After Kidney Transplant: GLP-1 Medication Study

We are testing whether GLP-1 receptor agonists can help reverse metabolic syndrome in patients on the kidney transplant waiting list. This study will evaluate changes in health and safety over 3 to 6 months.

Metabolic Syndrome in Kidney Transplant Patients3-6 monthsConfirmation phase (III)≤5 visitsNo PlaceboStandard MedicinesEndocrinologyNephrology

Lennox-Gastaut Syndrome: Carisbamate Treatment Study

We are investigating whether carisbamate can help reduce drop seizures in children and adults with Lennox-Gastaut Syndrome. This study will also look at the safety and tolerability of the medication.

Lennox-Gastaut Syndrome3-6 monthsConfirmation phase (III)6-10 visitsPost-Trial Drug AccessInvestigational MedicinesNeurology

Dapagliflozin for Heart Protection in Breast Cancer Patients

We are studying whether dapagliflozin can help prevent heart problems in breast cancer patients receiving chemotherapy. This trial compares its effects to a placebo over 12 months.

Secondary CardiomyopathyInvasive Breast Cancer3-6 monthsConfirmation phase (III)Standard MedicinesCardiologyOncology

Metastatic Colorectal Cancer: Atezolizumab with FOLFOXIRI

We are studying whether adding Atezolizumab to standard treatment helps patients with unresectable metastatic colorectal cancer live longer without disease progression. The trial also looks at the safety and quality of life for participants.

Metastatic Colorectal Cancer3-6 monthsConfirmation phase (III)No PlaceboStandard MedicinesGastroenterologyOncology

Pulmonary Sarcoidosis: OATD-01 Treatment Study

We are studying the effects of OATD-01, an oral medication, on reducing lung inflammation in people with active pulmonary sarcoidosis. The trial will also look at safety, lung function, and quality of life.

Pulmonary Sarcoidosis3-6 monthsEfficacy phase (II)6-10 visitsInvestigational MedicinesCost ReimbursementPartially RemoteInternal MedicinePulmonology

Fertility Treatments: Comparing Ovarian Stimulation Methods

We are studying two ovarian stimulation methods to see which one improves quality of life and satisfaction for women seeking fertility preservation or genetic testing. This research aims to help tailor treatments based on individual needs.

Subfertility3-6 monthsMonitoring phase (IV)No PlaceboInvestigational MedicinesEndocrinologyGynecology and Obstetrics

Ulcerative Colitis: Novel Rifamycin Enema

We are testing a new rifamycin solution for patients with mild to moderate left-sided ulcerative colitis. The study aims to see if it helps improve symptoms and induce remission compared to a placebo.

Left-Sided Ulcerative Colitis3-6 monthsEfficacy phase (II)6-10 visitsStandard MedicinesCost ReimbursementPartially RemoteGastroenterologyInternal Medicine