Search Clinical Trials in the European Union

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501-520 of 3,900 trials

Gastroesophageal and Pancreatic Cancer: New Imaging Technique

We are testing a new PET/CT imaging method to see if it improves cancer diagnosis and staging for patients with gastroesophageal and pancreatic cancer. This study aims to enhance comfort and effectiveness compared to standard imaging.

Pancreatic and Gastroesophageal CancerEfficacy phase (II)≤5 visitsNo PlaceboInvestigational MedicinesOncologyOtolaryngology

Efepoetin Alfa for Anemia in Chronic Kidney Disease on Dialysis

We are studying whether efepoetin alfa can effectively manage anemia in patients with chronic kidney disease on dialysis, compared to another treatment. This trial will also assess safety and quality of life for participants.

Anemia of Chronic Disease1-2 yearsConfirmation phase (III)>20 visitsNo PlaceboInvestigational MedicinesPartially RemoteHematologyNephrology

Breast Cancer-Related Lymphedema: Topical Tacrolimus Study

We are investigating whether a topical ointment can reduce swelling in patients with breast cancer-related lymphedema. This study compares the ointment to a placebo to see if it improves symptoms and quality of life.

Lymphedema1-2 yearsConfirmation phase (III)≤5 visitsPost-Trial Drug AccessStandard MedicinesPartially RemoteInternal MedicineOncology

Community-Acquired Pneumonia: Amoxicillin vs. Amoxicillin/Clavulanate

We are studying whether amoxicillin alone is as effective as amoxicillin/clavulanate for treating pneumonia in hospitalized patients aged 65 and older. This research may help determine the best antibiotic treatment for older adults.

Community-Acquired Pneumonia in Elderly Patients>2 yearsConfirmation phase (III)No PlaceboStandard MedicinesInfectious DiseasesPulmonology

Advanced Solid Tumors: BMS-986340 Treatment Study

We are testing a new treatment called BMS-986340, both alone and with other medications, for people with advanced solid tumors. The goal is to assess its safety and how well it may work against cancer.

Advanced Cancer>2 yearsSafety phase (I)Efficacy phase (II)No PlaceboInvestigational MedicinesOncology

Systemic Lupus Erythematosus: Upadacitinib Study

We are investigating whether the oral medication upadacitinib can improve symptoms in adults with moderate to severe systemic lupus erythematosus. The study will also monitor its safety over time compared to a placebo.

Systemic Lupus Erythematosus1-2 yearsConfirmation phase (III)>20 visitsPost-Trial Drug AccessStandard MedicinesCost ReimbursementRheumatology

Hidradenitis Suppurativa: Upadacitinib Study

We are testing Upadacitinib in adults and adolescents with moderate to severe Hidradenitis Suppurativa who haven't responded to other treatments. The goal is to see if it is more effective and safe than a placebo.

Hidradenitis Suppurativa>2 yearsConfirmation phase (III)16-20 visitsPost-Trial Drug AccessInvestigational MedicinesCost ReimbursementPartially RemoteDermatology

Advanced Cholangiocarcinoma: Futibatinib Study

We are studying the effects of futibatinib in patients with advanced cholangiocarcinoma with FGFR2 fusions or rearrangements. The goal is to see if it helps improve their condition and to understand its safety.

Cholangiocarcinoma6-12 monthsEfficacy phase (II)No PlaceboStandard MedicinesCost ReimbursementPartially RemoteOncology

Periodontitis: Vitamin D3 Supplementation Study

We are testing whether vitamin D3 can improve gum health in people with periodontitis and low vitamin D levels. This study will help us understand its effects alongside standard gum treatments.

Periodontitis6-12 monthsMonitoring phase (IV)≤5 visitsStandard MedicinesInternal MedicineOtolaryngology

Multiple Myeloma: JNJ-79635322 Study

We are testing a new medication for individuals with relapsed or refractory multiple myeloma or previously treated AL amyloidosis. The goal is to see how safe and effective this treatment is in humans.

Relapsed or Refractory Multiple MyelomaPreviously Treated AL Amyloidosis1-2 yearsSafety phase (I)HematologyOncology

Progressive Pulmonary Fibrosis: FAPI-PET Imaging Study

We are exploring if a special imaging method can help identify the type of lung condition in patients with progressive pulmonary fibrosis. This may improve how we understand and treat their disease.

Progressive Pulmonary Fibrosis3-6 monthsSafety phase (I)Efficacy phase (II)No PlaceboInvestigational MedicinesPulmonology

Prostate Cancer: Saruparib and Darolutamide Study

We are examining the effects of Saruparib and Darolutamide, both alone and together, in men with newly diagnosed prostate cancer. This research aims to understand how these treatments may impact patients before surgery.

Newly Diagnosed Prostate Cancer6-12 monthsSafety phase (I)OncologyUrology

Chronic Cutaneous Lupus Erythematosus: Anifrolumab Study

We are investigating whether anifrolumab can improve skin symptoms in adults with chronic cutaneous lupus erythematosus who haven't responded to other treatments. The study will compare its effects to a placebo over 24 weeks.

Cutaneous Lupus Erythematosus1-2 yearsConfirmation phase (III)11-15 visitsPost-Trial Drug AccessStandard MedicinesCost ReimbursementPartially RemoteDermatologyRheumatology

Preventing Hearing Loss: ACOU085 for Testicular Cancer Patients

We are studying whether ACOU085 can help prevent hearing loss in testicular cancer patients undergoing treatment with cisplatin. The trial will assess the safety and effectiveness of this treatment through ear injections.

Sensorineural Hearing Loss3-6 monthsEfficacy phase (II)≤5 visitsInvestigational MedicinesOncologyOtolaryngology

Aspirin for Preeclampsia Prevention in Twin Pregnancies

We are studying whether low-dose aspirin can help prevent preeclampsia in women expecting twins. This research aims to improve outcomes for mothers and their babies.

Preeclampsia6-12 monthsConfirmation phase (III)≤5 visitsInvestigational MedicinesGynecology and ObstetricsInternal Medicine

Fibrotic Interstitial Lung Disease: Morphine for Breathlessness

We are studying whether slow-release morphine can help reduce breathlessness and cough in patients with fibrotic interstitial lung disease. The goal is to see if it improves their overall quality of life.

Fibrotic Interstitial Lung Disease≤3 monthsMonitoring phase (IV)≤5 visitsStandard MedicinesCost ReimbursementPartially RemotePulmonology

Dementia Care: Benefits of Amyloid PET Imaging

We are exploring how amyloid PET imaging may improve care for people with dementia compared to standard diagnostic methods. This study aims to show its impact on important health outcomes.

Dementia>2 yearsMonitoring phase (IV)6-10 visitsNo PlaceboStandard MedicinesPartially RemoteNeurologyPsychiatry

Advanced Breast Cancer: Lasofoxifene and Abemaciclib vs. Fulvestrant and Abemaciclib

We are studying two treatment combinations for men and women with advanced breast cancer and an ESR1 mutation. The goal is to see which combination helps patients live longer without disease progression.

Metastatic Breast Cancer1-2 yearsConfirmation phase (III)Post-Trial Drug AccessNo PlaceboInvestigational MedicinesCost ReimbursementOncology

Severe Epilepsy: Cannabidiol Oral Solution

We are studying whether Cannabidiol can help reduce seizures in children and young adults with rare disease-related severe epilepsy. The trial also looks at safety and how it interacts with current medications.

Epilepsy3-6 monthsEfficacy phase (II)No PlaceboStandard MedicinesNeurologyPediatrics

Parkinson's Disease: Safinamide vs. Rasagiline for Fatigue

We are studying whether Safinamide or Rasagiline can help reduce fatigue in people with Parkinson's Disease already on stable treatment. The trial will also monitor safety and side effects over six months.

Fatigue in Parkinson's Disease3-6 monthsMonitoring phase (IV)No PlaceboStandard MedicinesPartially RemoteNeurology